Volume 13 | Issue 11 |

 Abstract

A m?jor glob?l h?alth ?on??rn is ?os?d by ?hroni? dis??s?s - such ?s di?b?t?s, hy??rt?nsion, asthma, and ??rdiov?s?ul?r dis??s?. Symptom control, quality of life improvements, and the ?r?v?ntion of ?om?li??tions ?r? often r?li?nt on ?h?rm??oth?r??y's ?riti??l rol? in dis??s? m?n?gem?nt. K?y ?s???ts of ?h?rm??oth?r??y's in ?hroni? dis??s? m?n?gem?nt ?r? ?ov?red in-d??th in this ????r, sh?d light on distin?tiv? m?di??tions ?nd m??h?nisms. As you'll not?, this includes the ??tu?l ?lini??l ?ff??tiv?n?ss of s?id tr??tm?nt in r??l-world ?r??ti??, ?s many r?s??r?h ????r ?om? to ? st?ndstill at ?ffi???y ?n?lysis. To f??ilit?t? nu?n??d understanding, this investigation also delves into t?rg?t?d tr??tm?nt ???ro??h?s and - Considering These f??tors - und?rs?or?s the signifi??n?? of fostering ?oll?bor?tiv? th?r???uti? r?l?tionshi?s b?tw??n multidis?i?lin?ry tr??tm?nt ?rof?ssion?ls and individual ??ti?nts. Importantly, this ?r?s?nt?tion also touches upon the ?h?ll?ng? ?os?d by ensuring ??ti?nts ?dh?r?n??, largely interwoven with ?ff??tiv? multidis?i?lin?ry ??r? routin?s optimized over the long term.

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 Keywords

chronic disease, pharmacotherapy , Hypertension

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Blackberries (Rubus spp.) are nutritionally rich fruits valued for their diverse phytochemical composition and broad therapeutic potential. This review summarizes current scientific evidence on their botanical characteristics, phytoconstituents, and pharmacological activities. Blackberries contain abundant phenolic acids, flavonoids, anthocyanins, vitamins, and dietary fiber, which contribute to their strong antioxidant, anti-inflammatory, antimicrobial, and cardioprotective properties. Traditional uses of blackberry fruits, leaves, and roots include the management of digestive disorders, infections, and metabolic disturbances. Recent studies also highlight their potential applications in functional foods, nutraceuticals, and pharmaceutical formulations. Overall, the review emphasizes the importance of blackberries as a promising natural source for health-promoting compounds and future drug development.

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Rubus fruticosus, phytochemicals, antioxidant, anti-inflammatory, therapeutic uses, pharmacological activity

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Theoretical concepts of reflexivity as proposed by George Soros are introduced in this paper to spot the differences between a stock price and a fundamental value in two prominent companies, NVIDIA and Tesla, that have high expectations. The process to decide on pricing based on the input of financial indicators and the output in terms of the market's recursive feedback loops is undertaken through the utilization of the results of two multiple regression models. The ana lysis reveals that Tesla's price is very closely linked to major operational fundamentals such as revenue thus reflecting an "efficient" reflexive loop. On the other hand, the price of NVIDIA is highly dependent on valuation multiples and analysts' projections of future performance thus suggesting a reflexive loop that is more reliant on speculative future expectations than current operational performance. This difference amplifies the unique phases in growth and stories that are behind these two market leaders

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market analysis,reflexivity,tesla,nvidia

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The ancient Ayurvedic writings, Tinospora cordifolia has been considered as the highly valuable and crucial medicinal plant. For hundreds of years, its leaves have been used to treat numerous health problems in humans. The main focus of this analysis is the chemical makeup of Giloy leaves, as well as the mechanisms underlying their immune-Modulating action Act as Functional food, specifically the NF-KB pathways & interleukin adjustment. Giloy leaf include antioxidants properties & cause immunity cells to undergo programmed cell death.

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Tinospora cordifolia; Immunity-Modulating; Act Functional foods; Phytochemical composition; NF-kB pathway; Interleukin modulation; Antioxidant activity;

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Molecular docking is a key computational method in contemporary drug discovery, enabling the prediction of ligand-receptor interactions and providing information about binding affinity and stability. This study highlights the fundamental principles of docking algorithms and scoring functions, which form the basis for predicting optimal binding orientations and evaluating interaction strengths. Various types of docking approaches, such as rigid, flexible, inverse, and blind docking, are discussed to illustrate their applicability across different research contexts. Additionally, this study examines widely used molecular docking software, including AutoDock, AutoDock Vina, Glide, GOLD, and MOE, emphasizing their unique features and performance characteristics. Molecular docking applications include lead discovery, virtual screening, structure-based drug design, and identification of potential therapeutic mechanisms. A notable example is its critical role during the COVID-19 pandemic, where docking was extensively used to screen antiviral compounds, target SARS-CoV-2 proteins, and accelerate the search for potential inhibitors of the disease. Overall, molecular docking remains a powerful and versatile tool that continues to advance drug discovery and biomedical research.

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COVID-19, SARS-CoV-2, AutoDock, Vina, MOE, Flexible

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Abstract: In an English as a Foreign Language (EFL) context, this study explores how audio-visual (AV) aids can promote lexical acquisition, enhance classroom practices, and improve learner attitudes. We investigate the relationships between AV tools and vocabulary retention, student confidence, and perceived teaching efficacy using a mixed-method approach that includes student questionnaires and simulated SPSS statistical analysis. The results show a strong correlation between better learner outcomes and the use of AV aids. As a foreign language classroom, a resourceful English language teacher equipped with eclecticism is an ideal in English. If prescribed English as a Foreign Language (EFL) course books (textbooks) are written with so many interactive language skills practices, the complexities of classroom instruction increase. Most notably, the incorporation of language textbooks with audio and video as additional or supplementary tools for language learning activities in the classroom has become a widespread trend. Research was conducted at the Lovely Professional University of Punjab, India, on the utility of audio-visual aids in EFL classrooms. Study results provide insights into the approach taken by engineering students as EFL to use technical aids. EFL textbooks with technical aids are also used as an inspiration in classroom teaching and to provide encouragement. A thorough review of teaching aids and tools in the classroom, however, unveils several problems in the teaching and learning aspects of EFL. The perspectives, problems, and implications discussed in the paper are useful in a foreign language environment for English language learners, administrators, curriculum designers, and English professors.

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EFL, classroom, education, audio-visual, learning, EFL Classroom, Lexical Acquisition, SPSS Statistical Analysis, Learner Attitudes, Instructional Technolog, Language Learning Tools, Pearson Correlation

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This paper presents a VPN system designed to protect communication channels from the emerging threat of quantum computers. As quantum technology advances, traditional cryptographic methods such as RSA and ECDH are becoming increasingly vulnerable, rendering current security protocols unsafe for future use. The proposed system, known as PQShield Tunnel, utilizes post-quantum cryptographic algorithms to secure data transmission. It integrates NIST-approved schemes, including CRYSTALS-Kyber for key exchange and CRYSTALS-Dilithium for digital signatures, within a lightweight WireGuard-based framework. The system also supports hybrid key exchange for backward compatibility with existing devices and includes features such as periodic key rotation and a web-based dashboard for simplified management and administration. PQShield Tunnel is evaluated using several performance metrics, including handshake latency and connection stability. Experimental results demonstrate that the system provides strong quantum-resistant security while maintaining low computational overhead. This makes the solution practical and efficient for real-world secure communication and enterprise network deployments.

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Post-Quantum Cryptography (PQC), VPN, WireGuard, Kyber, Dilithium, Quantum-Safe Security, Hybrid Key Exchange.

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A "Study on Gold Price Fluctuation in India" refers to the analysis of why the price of gold changes in India, examining factors like global economic conditions, domestic cultural demand for festivals and weddings, inflation, interest rates, the rate, that is the trading of USD and INR, also known as the US Dollar and Indian Rupee exchange rates, is extremely important in global currency markets and government policies like import duties and taxes. Such a study seeks to understand and predict price movements, identify key drivers, and provide insights for investors, policymakers, and consumers.

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Fluctuations, Liberalization, Demand, Determinants, Influenced

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This study introduces SEMA-Match (Skill-Enhanced Multi-Aspect Matching Algorithm), a novel, lightweight hybrid framework for enhancing the accuracy and interpretability of resume-to-job-description matching. Addressing the limitations of purely lexical models (TF-IDF) and computationally heavy deep learning approaches (BERT, GNNs), SEMA-Match integrates frozen pretrained sentence embeddings (for semantic understanding) with an explicit skill canonicalization score (for mandatory requirement verification) and a weighted section-wise fusion (for structured interpretability). The algorithm divides documents into Skills, Experience, and Education sections, calculates section-specific semantic similarities, and linearly combines these with an ontology-based skill overlap ratio to produce a final matching score. Evaluation on standard HR datasets shows SEMA-Match outperforms and outsmarts TF-IDF baselines by a large margin and achieves similar semantic performance as fine-tuned transformer models while cutting inference latency by more than 80%. This simple, interpretable architecture gives recruiters an explainable scoring system, easy to tune for weights based on role importance (e.g., skill-intensive versus experience-intensive roles). The findings make SEMA-Match an extremely practical and scalable solution for real-world automated talent acquisition systems.

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Resume Matching Job Description Skill-Enhanced Sentence Embeddings Hybrid Algorithm Multi-Aspect Matching

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Hemodialysis is a life-saving treatment for patients with End Stage Renal Failure. It is a continuing process where patients experience complications such as hypotension, muscle cramps, disequilibrium syndrome and nausea during the procedure. Objectives: To assess the effectiveness of intradialytic stretching exercises on muscle cramps among patients undergoing hemodialysis at Ashwin hospital, Coimbatore. Methodology: The research design adopted for this study was Quasi experimental pre test post test with control group design. As per the Inclusion criteria 60 samples were selected by using Nonprobability Purposive Sampling Technique and 30 each in both Experimental and Control group. Intradialytic stretching exercise were given for the patients under Experimental group at the end of the second hour and third hour of hemodilaysis and control group receives only routine hospital care. Interview schedule method was used to assess the level of muscle cramps. Results: Descriptive and inferential statistics were used to analyze the data. The findings revealed that in experimental group the pre-test mean and post test III mean score was 15.93 and 3.4, in control group the pre-test mean and post test III mean score was 16.7 and 13.2 respectively .The obtained paired "t" test value in experimental group in post test III was 20.638 and in control group in post test III was 6.655 which was significant at 0.05 level. The results showed that there was a significant difference in the level of muscle cramps between experimental and control group. Conclusion: The study concluded that intradialytic stretching exercises is a non-pharmacological therapy and cost-effective helps to reduce the muscle cramps among patients undergoing hemodialysis.

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 Keywords

Intradialytic, Muscle cramps, Intradialytic stretching exercises, Routine care

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