Volume 12 | Issue 12 |

 Abstract

The dynamic nature of diseases requires flexible approaches to health and treatment, especially for emerging conditions like amoebic meningitis caused by Naegleria fowleri.This article explores the Ayurvedic concept of Anuktha vyadhi (unspecified diseases), which accommodates the evolution of new diseases through principles derived from texts such as Charaka Samhita and Susrutha Samhita. Ayurvedic frameworks like Adidesha and Arthapatti1 enable the adaptation of classical principles to modern pathologies. Amoebic meningitis, or Primary Amoebic Meningoencephalitis (PAM)2 , is a rare and fatal brain infection often contracted through exposure to warm freshwater contaminated with N. fowleri. Its rapid progression from fever and meningismus to seizures and coma, coupled with a high mortality rate, underscores the urgency of exploring both modern and traditional approaches to understanding and managing this disease. Modern diagnostic techniques, such as CSF analysis and PCR, alongside antifungal therapies, are highlighted for their clinical relevance. The article draws a conceptual parallel between Primary amoebic meningoencephalitis and Ayurvedic conditions like Shleepada and Mastishka jwara, emphasizing similarities in symptoms, causative factors and pathogenesis. Ayurvedic principles such as the involvement of aggravated Kapha and Pitta, explain the inflammation and obstruction observed in PAM. Additionally, the Shleepada nidana in Ayurvedic texts closely aligns with the environmental risk factors for PAM, such as exposure to stagnant or contaminated water. Treatment considerations in Ayurveda, including Sira vyadha and Roga-Rogi pareeksha (disease and patient examination), are discussed as potential complementary approaches. By integrating insights from Ayurveda with modern medical practices, this article advocates for a holistic understanding of rare and emerging diseases like amoebic meningitis, bridging ancient wisdom and contemporary science.

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 Keywords

Anuktha vyadhi, Primary amoebic meningoencephalitis (PAM), Shleepada

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A new efficient procedure for the synthesis of 9(2-chlorophenyl aridine) under microwave irradiation and derivatives were characterized by different spectral technique IR and NMR spectroscopy. Reactions proceed with very good to excellent yield at room temperature. Further were screened for their in vitro antibacterial activities against pathogenic bacteria such as Salmonella typhi, Proteus vulgari, Klebsiella pneumonia, E. Escherichia, Shigella Flexner (gram -ve) and Staphylococcus area (gram +ve) bacteria by using agar-agar well diffusion meth- od. The results were evaluated after 24 hour of incubation. Chloro-substituted compounds showed antibacterial activity values in the low microbial range.

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Keywords: Acridine, spectral analysis, antibacterial efficacy.

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Digital is growing, print is declining. By the time the standard newspaper lands at the front door the next morning, the headlines have already been covered online by multiple digital media outlets. The rustle of turning pages, the inky scent of fresh print-these are sensory hallmarks of the traditional newspaper. The best qualities of a printed newspaper is its tangibility, credibility and trustworthiness. The fate of newspapers in the present era is a topic of much debate and speculation. In the age of instant information, a question arises: Are newspapers destined to become relics of bygone era, eclipsed by the vibrant glow of online news sources? Reasons for the decline of print includes rising costs, declining advertising revenue, reduced readership etc. But we cannot conclude by saying that print is useless because the future of newspapers is likely to be a hybrid model that combines print and digital elements. Some potential scenarios for the future newspapers include niche publications, community newspapers, digital-first approach. While Print newspapers are facing challenges due to the rise of digital media, they are not entirely obsolete. They continue to hold a special place in our hearts and minds. In conclusion, Print is not useless, but it's USP isn't as strong as that of Digital journalism.

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 Keywords

Transition, Fate, print Media, Digital Advancements, Journalism, Future Trends.

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Osteoarthritis also known as degenerative joint diseases .Osteoarthritis of knee commonly known as wear and tear arthritis because the natural cushioning between joints and cartilage wear away. Due to this, the bones of the joints rub more closely against each other, so the shock absorbing benefits of cartilage is lost in a great way and progressively it may lead to disability. It is believed to be the fourth leading cause of disability in the world. The prevalence of Osteoarthritis rises strikingly with age as it is weigt bearing joint. Osteoarthritis is uncommon before the age of 40 and highly prevalent over the age of 60.Therefore it is most common in elderly. It is more common in women than in men. It is also common in persons who are involved in physical labour.

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osteoarthritis, homoeopathy, therapeutics, 2nd prescription

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Abstract: Fabric waste has become a pressing environmental concern, with the global fashion industry contributing significantly to the problem. Patchwork, a time-honoured craft, offers a creative and sustainable solution to fabric waste. This paper explores the historical roots of patchwork, its evolution in fashion, and its potential as a sustainable practice in modern textile production. By examining case studies and current practices, we aim to establish patchwork as a viable strategy for reducing fabric waste and promoting sustainable fashion. By exploring its formal beauty and use in women's clothing design, the research provides innovative ideas for advancing sustainability and artistic expression in the textile industry.

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Keywords: Patchwork; Fabric Recycling; Women's wear Design.

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The steel-and-concrete structure is a contemporary design that combines the benefits of both steel and concrete. It is used extensively worldwide these days. Understanding and putting this kind of organization into effect requires a thorough understanding of its genesis and development history. The analysis of shear-key hybrid connections between steel columns and RC beams is the focus of this paper. This study addresses six models in total: the entire reinforced concrete structure, the relationship of reinforced concrete beams to steel columns, and the steel structure of two distinct seismic zones, Zone II and Zone V. Considering the 36 x 36 m plan size of the G+21 building for each of the six types. Complete RC and steel structures are generic models that do not take replacements into account, but in RC beam to column structure by installing shear keys at every RC beam to steel column connection, we are swapping out all of the peripheral concrete columns for steel ones. Comparing the drift, displacement and stiffness parameters of the models under consideration at two distinct seismic zones is the primary objective of the research. Response spectrum analysis is used to analyze the Base shear, which is then compared to the structures. ETABS-2021 is utilized in this project for entire model design and analysis. The analysis is done as per IS 456:2000 code and for seismic analysis IS 1893:2016 (part 1) code. M30 grade of concrete and FE-550 grade of steel is adopted. Based upon the results as plotted on the graphs it is clear that RC beam to steel column connection structure performing better compared to RC and Steel Structure in terms of Storey Drift and Storey Displacement values in both the zones II and V. The base shear is little high in RC structure compared to RC Beam to steel column structure but, it doesn't affecting much in structural aspects. RC Beam to Steel Column Structure is Stiffer as well as Economical.

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Hybrid connections, steel columns, reinforced concrete beams, shear-keys, Bracings

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In this study, we propose a system to develop an efficient model for timetable scheduling utilizing a genetic algorithm. The goal of the research is to construct a model leveraging genetic algorithms to effectively address complex combinatorial optimization problems. The algorithm was evaluated on both small and large problem instances. The performance of the algorithm was notably improved through modifications to the fundamental genetic operators, which prevented the generation of new conflicts within individuals. The scheduling solution outlined in this paper is adaptive in nature

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genetic algorithms, scheduling

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Multiferroic, Nanopowders, BiFeO3, Ba and Ca dopants, SCM, applications

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This research paper investigates the state of instructional facilities in various colleges of higher education in Odisha, India, highlighting their role in shaping student learning outcomes and overall educational quality. The study employs a mixed-methods approach, combining quantitative surveys and qualitative interviews to assess the adequacy and availability of essential instructional resources, including classrooms, laboratories, libraries, and digital learning tools. The findings reveal significant disparities in the provision of these facilities between urban and rural institutions, with urban colleges generally offering superior resources. This disparity impacts student engagement, academic performance, and overall satisfaction. The study emphasizes the urgent need for policy interventions and targeted investments to enhance instructional facilities, particularly in under-resourced institutions. By providing insights into the current status of instructional facilities in Odisha, this research aims to inform stakeholders and support initiatives aimed at improving educational environments and outcomes across the state.

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Instructional facilities, higher education, educational quality, student engagement, urban-rural disparity

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Background: Prolonged standing, over pronation, High-Arched Feet, Leg-length discrepancy, improper footwear and increased BMI may contribute to plantar fascitis. Myofascial release applies pressure to change the fiber length. Increased tissue elasticity allows more movement with fascia tissue and prevents restrictions and adhesions from occurring. Stretching focused on gastrocnemius and soleus muscles is effective because it increases Achilles' tendon flexibility which in turn reduces the tensile forces applied to the plantar aponeurosis. Ultrasound therapy helps to relieve pain by increased local metabolism, circulation and extensibility of connective tissue and tissue regeneration. Hence the purpose of the study is to compare effectiveness of Self Myofascial release and stretching with both in the combination of ultrasound therapy in reducing the pain and improving the range of motion and functional ability in patients with plantar fascitis. Methods: A total of 50 samples were taken from outpatient physiotherapy department, AVMC&H, and Puducherry. They were divided into 2 groups - Group A and Group - B (25 subjects in each group). Group A received Self Myofascial release with ultrasound therapy and Group B received stretching exercise with ultrasound therapy for a period of 4 days a week for 2 weeks. Prior to the study, the objectives and guidelines were explained to all the participants and written informed consent form and information form were signed by the participants. The pretests and posttests Foot Function Index scale and ankle range of motion using Universal Goniometer were recorded before and after the intervention of 2 weeks. Results: The results of the study were significant improvement in Self Myofascial release with ultrasound therapy was much better than stretching exercise with ultrasound therapy. Conclusion: The study concluded that the self-Myofascial release with ultrasound therapy were effective in reducing the pain and improving range of motion and foot function in patients with plantar fascitis.

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 Keywords

Plantar fascitis, Myofascial release, stretching, lacrosse ball, ultrasound therapy.

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Creative Commons Attribution 4.0 and The Open Definition