Volume 8 | Issue 3 |

 Abstract

Regenerative medicine uses MSC as a tool to promote tissue regeneration. A major action of MSC to repair pathological degeneration is secreting paracrine secretory factors to reduce inflammation and accelerating tissue regeneration. MSC from different origins produce different significant trophic factors. Using MSC that fits to the need is a strategy for regenerative therapy. Here, we investigated paracrine bFGF TGF-? and IGF, as significant secretory factors, in MSC derived from human amniotic fluid (AF-MSC), Wharton�s jelly (WJ-MSC) and endometrium. The work quantified the levels of bFGF TGF-? and IGF gene transcriptions using quantitated real time RT-PCR and the secretory levels of trophic factors using ELISA assay. Our results indicated that bFGF was a significant trophic factor secreted by AF-MSC, whereas, TGF-? was a significant factor in WJ-MSC. AF-MSC secreted bFGF at 3 times over to control human fibroblasts. Secreting of IGF binding protein was found at a low level in AF-MSC, WJ-MSC and EM-MSC as compared to the secreting of control human fibroblast. Moreover, we found that WJ-MSC at late culture had a high level mRNA transcribed in bFGF TGF-? and IGF genes. They showed 2 times of bFGF and TGF-? genes expression and 7 times of IGF-1 gene expression higher than control. However, our study in allelic expression of IGF-2 imprinted gene analysis indicated epigenetic imbalance in WJ-MSC at late cultured passage. We conclude that an optimal MSC type for treatment in different pathologic diseases should be provided regarding a dissimilar significant trophic factor of each MSC origin. We also suggested that MSC in late cultured might great offer in regenerative medicine as cell-free therapy.

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 Keywords

amniotic fluid, endometrium, growth factors, paracrine, regenerative medicine Wharton�s jelly

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Students Attendance gadget is smart way of marking attendance. This work describes the methodology where attendance of students is taken with the aid of capturing the photograph of the school room and with the aid of detecting and recognizing the faces of college students and matching it with the database and marking attendance. This approach overcomes some of the drawbacks of the guide attendance system and additionally we can have a view of the file of attendance of students enrolled for that specific class.

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 Keywords

Automated, Attendance, System, Student, Technology

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Creative Commons Attribution 4.0 and The Open Definition

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This study examined gender and locality differences on anxiety and gender role conflict with 600 Mizo adolescents aged between 15 to 18 years (300 males, 300 females and 300 urbans, 300 rural), from different districts of Mizoram. The participants were tested using Gender Role Conflict Scale (GRCS) and Depression Anxiety Stress Scale- 42 (DASS- 42) in classroom settings. The findings of the present study show significant independent effect of gender and locality on anxiety, in which female participantsas compared to male participantsscored higher on anxiety; and urban participants as compared to rural participants scored higher on anxiety. Also, rural participants scored higher than urban participants on restrictive emotionality and restrictive affectionate behavior between men/women subscales of GRCS, whereas, the urban participants scored higher than the rural participants on conflict between work and family relations subscale of GCRS.

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 Keywords

Anxiety, gender role conflict, success, power, and competition, restrictive emotionality, restrictive affectionate behavior between men/men, conflict between work and family relations.

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Creative Commons Attribution 4.0 and The Open Definition

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Regenerative medicine is a strategy of treat degenerative pathology. Mesenchymal stem cell (MSC) has been used as tool for tissue regeneration. Both MSC embedding in scaffold and MSC from microfracture techniques are presented by previous study for regeneration at site of cartilage injury. To studied and compare cartilage regeneration by MSC embedding in scaffold and microfracture techniques, we contributed a cartilages defect rabbit knee using a stainless steel drill. PEGDA-scaffold, which was embedded with MSC was implanted over the left knee lesion, whereas, the injured right knee was drilled deep into subchondral bone for leaking of bone marrow-MSC. Rabbits were sacrificed at 12 weeks after surgery to examine macroscopic appearance of the articular following the modified ICRS evaluation. Macroscopic appearance was evaluated by immunohistochemistry. We found that cartilage repairs with the uses of microfracture technique showed a better result as compared to the uses of MSC/PEGDA scaffold implantation technique, as seen in ICRs scores. The treatment with microfracture technique improved smooth cartilage surface, subchondral bone formation and reduce inflammation in rabbit knee. We conclude that microfracture technique is an efficient treatment for tissue regeneration in knee injury.

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Histopathology, Knee injury, Mesenchymal stem cell, Scaffold

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Abstract: The paper entitled as �a study on evaluation of financial performance analysis of North � Western Road Transport Corporation�. The objectives of the study are mainly focused on analyzing the performance of finance which is revealed through profit/loss position of the concern for the study period. All the components which are influencing the financial strength could be analyzed. The study covers only last ten years statement which if 2008-09 to 2017-2018. The data collected from the study were secondary data was collected from annual report, department manuals brochures mainly from balance sheet and mainly from website. From the analysis, findings and recommendations were drawn to improve the performance of Equities North � Western Road Transport Corporation.

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financial performance

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Creative Commons Attribution 4.0 and The Open Definition

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Gandhi and Macaulay both were philosophers and their philosophies are still relevant. Thomas Babington Macaulay, better known as Lord Macaulay, is the man who brought English language and British education to India. Mohandas Karamchand Gandhi gave us the first indigenous education system named Basic Education in the British Raj. The foreign education system makes the Indian weak and fragile. Instruction in the foreign language decreases critical thinking as well as prepares the common masses to follow the guidelines laid down by the Britishers. It took many years for the Indians to overcome the trauma inflicted by their colonizers. The retaliation of the colonized to their colonizers can be seen in the Basic Education of 1937 laid down by M.K. Gandhi in which he had given them the hope of freedom and sovereignty. Gandhi knew that education plays a very effective role in the awakening of Indian masses. He worked even before the Wardha Commission as Britishers were also working on the education of Indians before the Macaulay minutes. This Basic Education or Wardha Commission or The �Nai Talim� creates a sense of unity and interdependence among fellow Indians by giving the concept of vocational education that was purely indigenous.

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Macaulay�s Minutes, Basic Education, Wardha Commission, �Nai Talim�

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Creative Commons Attribution 4.0 and The Open Definition

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Artificial intelligence is defined as developing computer programs to solve complex problems by applications of processes that are analogous to human reasoning processes. It is that branch of computer science that studies and develops intelligent machines and software.This paper is a survey which contains emerging of the technology, AI Design Models and also k-means algorithm.

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Artificial algorithm , AI Design Models, k-means algorithm and clustering algorithm.

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Creative Commons Attribution 4.0 and The Open Definition

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ABSTRACT - Fog and haze make the photo degraded, and seriously affect the ordinary operation of the records device inside the fields of military, transportation and protection monitoring. Under this condition, the image de-fogging is of great significance. In order to meet the needs of real-time processing of existing video's de fogging process, a recognition algorithm based on recurrent neural network is proposed in this project. We use sparse automatic coding machine to extract the texture features of the image, and extract all kinds of fog related color features. Then, we use the recurrent neural network to implement sample training process, and we obtain the mapping relationship between texture structure features and color features and scene depth, and then we estimate the scene deep map of fog images. Finally, the atmospheric scattering model is used to recover the fog free image according to the scene deep map. Experiments show that the proposed algorithm can effectively obtain the scene depth of the image, and recover the ideal fog free image

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Recurrent neural network, Video image, de-fogging recognition algorithm.

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The penetration of smart phones is making things easy and approachable for everyone as with single click things can be arranged. Today the people are using digital platform and have started using online food ordering app to get the food promptly. This paper studies the effect of demographic profile on online food delivery services and how these companies uses the social media as a promotional tool. The paper also finds the impact of social media in the promotion of the food delivery companies. The 179 online food app users are chosen. It was found that majority of the respondents are aware and use these apps, avail the benefits of these apps, order food on a regular basis, certain factors which they consider most important in an app, This study will help the marketer to understand the utility of the promotion done in these social media sites like Facebook, Twitter, Instagram, You Tube, Pinterest.

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Social Media, Food delivery companies, Marketer, Promotion, Youth

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Creative Commons Attribution 4.0 and The Open Definition

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Abstract : Development comes with a cost and is apt for the state of Jharkhand where the people are undergoing several health issues caused by the polluted air, water and land. The residual effluent from the industries has depleted the quality of land where agriculture is the major source of income for many people of the State. People think twice before consuming water from natural water basin, even the underground water is not in its pure form. Talking of people who are unaware of the health problems and consume the polluted water from any source is self-inviting water-borne diseases.

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 Keywords

SUSTAINABLE DEVELOPMENT, SUSTAINABLE DEVELOPMENT GOALS (SDG), JHARKHAND, CSR, CORPORATE SOCIAL RESPONSIBILITY, HEALTH, DRINKING WATER, SANITATION

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Creative Commons Attribution 4.0 and The Open Definition