Volume 11 | Issue 5 |

 Abstract

Hemoglobin is a major protein involved in transport of oxygen. Hemoglobinopathies are group of disease characterized by quantitative and/or qualitative abnormality in the production of Hemoglobin, e.g. thalassemia and sickle cell disease respectively. Identification of these disorders is immensely important epidemiologically and they can be prevented by population screening. Approximately 250 million people constituting 4.5% of the world population carry a potentially pathological haemoglobinopathy gene. Beta thalassemia are widely distributed through a belt running from Mediterranean, North West Africa through the Middle East, Pakistan, India and south East Asia. Hbs is prevalent in Africa, Mediterranean countries, and India. The disease is observed in Orissa, Andhra Pradesh, some tribal areas of Madhya Pradesh, Tamilnadu and Maharashtra. In USA and Latin America countries, 6-8% of the black carry sickle cells gene. The aim of the study was study of various Hemoglobinopathies in patients of Gujarat.

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Akila Y. Dhariya

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As price of fuel increasing, running cost of the electric vehicles is less than that of gasoline powered vehicles. it is difficult to use internal combustion engine vehicles. The future of automobile is going to be electric. The pollution emitted by the automobiles is increasing rapidly nearly about 73% of total pollution due to the usage of internal combustion engines. If go for newly launched electric vehicle, they are highly priced compare to conventional IC engine vehicle. Battery used by these EVs are costlier, they use lithium-ion batteries which prices around thousands. Obviously, everyone is looking towards making electric vehicles pocket friendly. There is a method of doing this is to converting an internal combustion engine (ICE) vehicle into an electric one. An electric vehicle is a type of vehicle that uses electric motor and battery pack instead of an internal combustion engine. Power is given from battery pack rather than petrol. This saves money and has smaller impact on the environment as well. There are few barriers for the rapid adoption of electric vehicles, like lack of charging infrastructure, limitations of battery technology and high purchase costs. In this project, we are going to converting a petrol bike into electric bike using lithium-ion battery and BLDC motor.

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Electric Vehicle, Electric Battery, Lithium-Ion Battery

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Introduction: Dobutamine stress echocardiography (EDobu) is a non invasive examination used to detect myocardial ischemia and to estimate viability. However, it is not without risk. Case report: A 79-year-old patient with cardiovascular risk factors such as type 2 diabetes on oral antidiabetic drugs, hypertension on calcium channel blockers and dyslipidemia on statins, who has been suffering from angina class II of CCS for 5 years. The clinical examination and the ECG of the patient were without particularity. The transthoracic echocardiography was normal, hence the indication for EDobu. At the beginning of the test, the patient was asymptomatic and hemodynamically stable. During the examination, at the beginning of the 30-gamma dobutamin, at the peak of stress, the patient presented typical chest pain with a persistent ST-segment elevation in the inferior territory and kinetic disorders in the same territory. The patient was sent directly to the KT room where a coronary angiography was performed coming back in favor of an occlusion of the proximal right coronary stented successfully. DISCUSSION: Stress echocardiography is the combination of 2D echocardiography with a physical, pharmacological, or electrical stress . The diagnostic endpoint for the detection of myocardial ischaemia is the induction of a transient change in regional function during stress. Serious complications remain exceptional, particularly for stress echo. the occurrence of an acute coronary syndrome during a dobutamine stress echocardiography remains very rare. the incidence of SE-related deaths estimated at < 0.01%, and the incidence of myocardial infarction in the range 0.01-0.1%. Stress Echo may predispose to AMI by either mechanical means by increased shear forces in the coronary artery resulting in plaque disruption or by a biologic process with direct or indirect effects of dobutamine on thrombus formation by a signifiant direct platelet activation. Also, Dobutamine induce an alpha1-mediated coronary vasoconstriction and it is considered a mechanism for developing acute myocardial ischemia. in certain registers such as the POLstress register and the series of cases by and Picano et al and the UK registry, the occurrence of acute coronary syndrome during the stress echo remains rare and does not exceed a value between 0.06 and 9.4% depending on the registers/ Conclusion: EDobu is an important examination in the detection of coronary artery disease that requires close monitoring of the patient and compliance with indications and contraindications.

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Stress echocardiography, Dobutamine, Acute coronary syndrome

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Augmented reality is a technology in which a person's conception of reality can be enhanced, typically through augmented sound, video or graphics displays. The augmentation is typically implemented via various technologies, such as a headset that may be worn by the person. One or more augmented views may be presented to the person through the headset. Augmented reality actually superimposes virtual objects into the real environment with the real objects for enriching the viewer's experience Augmented reality with virtual reality in virtual space, also enhances the audience perception by displaying additional information. Due to the increase of interest in Augmented Reality (AR), the potential uses of AR are increasing also. It can benefit the user in various fields such as education, business, medicine, and other. Augmented Reality supports the real environment with synthetic environment to give more details and meaning to the objects in the real word. AR refers to a situation in which the goal is to supplement a user's perception of the real-world through the addition of virtual objects. This paper is an attempt to make a survey of web-based Augmented Reality applications and make a comparison among them.

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Augmented Reality, Virtual object, ARSC

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To days the nature of environment pollution is the major issue. The pollution will occur due to electricity generation and IC engine vehicle. We try to reduce it with the help of electric vehicle are types. They are the, HEV, EV. We introduce new type of they are REV (Regenerative Electric Vehicle) they have generate electric with itself to drive. REVs we are trying to get electricity from charging are less and also not. This is the type of new electric vehicle In this model we have study to the electric regeneration in electric vehicle the production of electricity will be start on second wheel of they have using in this as a dummy wheel the production of electricity will be produced with the help of generator in this model the generator will be generate electricity this store in second battery if the second battery will be charge fully then we have directly change with or replace with first battery due to eat charging frequency will be reduce of electric vehicle

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REV - Regenerative Electric Vehicle

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Manilkara hexandra tree is critical for the environment and human beings, so there is an pressing need to conservation this tree species. it is local of India, located within the forests of Madhya Pradesh, Gujarat and Rajasthan. its fruit fit to be eaten and nutritional. its useful wooden, latex and bark and contributes huge livelihood aid to nearby inhabitants. the existing observe become accomplished in Districts Meerut and Bulandshahr from may 2018 to September 2022. The mature, dried and healthful seeds of Manilkara hexandra had been accumulated from Meerut. Seeds had been sown in pots containing aggregate of soil : manure 3:1 ratio. The germination started out seven days after sowing inside the month of May. the entire germination possibilities were found 95 % inside 21 days during summer time month. Manilkara hexandra plant 365 days old saplings plantation and dispensed to the regions of districts Meerut and Bulandshahr. The status of Manilkara hexandra saplings increase and improvement of all stages. I had recorded four years growth of Manilkara hexandra tree species height 362.78 cm in I P college,Lalita Prasad Saraswati Balika Vidya Mandir and Mohan Kuti Ashram Bulandshahr. it concluded at the intention of the existing observe is to unfold cognizance towards the conservation of the uncommon beautiful tree species Manilkara hexandra in Meerut and Bulandshahr districts. The goal of Manilkara hexandra plantation that benefited to surroundings and humans of those areas, in which the species is rare and no longer observed

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Manilkara hexandra, Nutritional, Rare, Conservation, Meerut, Bulandshahr

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Chronic renal failure (CRF) is a growing problem worldwide leading to increasing incidence of life threatening complications or death. Over 1.1 million patients are to have renal failure worldwide with and annual increase at a rate of 70%. CKD in India is an important public health problem. The main contributing factors for high prevalence of CKD in India are hypertension and diabetes mellitus. Kidneys are those vital organs of the body responsible for diverse body function. Chronic Kidney Disease (CKD) is a condition characterized by permanent and significant loss of the glomerular filtration rate (GFR). The main stay of treatment in this condition is renal replacement therapy which includes both kidney transplantation and dialysis (Hemodialysis and peritoneal dialysis). In hemodialysis, anticoagulant is necessary to prevent blood clots within the extracorporeal circuit. Prothrombin time (PT) and activated partial thromboplastin time (APTT) are screening tests for extrinsic, intrinsic and common pathway clotting factors. The aim of the study was investigating the coagulation profile pre and post hemodialysis in CKD patients compared to normal control.

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Chronic Kidney Disease, Hemodialysis, Coagulation profile (PT, PT-INR, aPTT)

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Supply chain performance plays a critical role in the success of businesses across industries. In recent years, the rise of cloud-based data warehousing platforms has introduced new opportunities for organizations to improve supply chain operations through better data management and analysis. This current dissertation work examines the use of Snowflake Data Warehouse for optimizing supply chain performance. Through a review of literature and analysis of case studies, the paper presents the key features and benefits of Snowflake including cloud technologies, and discusses how it can be integrated with other systems and technologies to support supply chain decision-making and drive performance improvements. The results of the study suggest that Snowflake can be a valuable tool for improving supply chain performance, and offer insights, recommendations and prediction for organizations/business looking to implement and can be visualize in the form of graphs and charts to support quick decision making to the business users.

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Machine learning techniques, Cloud storage, Snowflake data warehouse, Visualizations, Data Analysis.

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The availability of clean, drinkable water is currently under a growing amount of pressure. Due to government inefficiency and the nation's growing population, this issue is particularly prevalent in rural areas. As a result, this particular project's wireless, multi-sensor network seeks to detect and show the water's physicochemical quality in real-time in a way that is far more affordable than the present methods, which include sampling and laboratory tests. It considers a number of variables and displays this real-time quality by showing the electrical conductivity, pH, total dissolved solids (TDS), turbidity, and temperature of the water that is being evaluated. Additionally, this remote-control system was created especially for bodies of water like lakes, reservoirs, rivers, etc. where it is impossible to check the water quality Because water properties vary at every place, it is impossible to operate a fixed system in such complex scale water settings. To prevent this, we created a boat that can float and be controlled by the user to go on the water. This building is shaped like a hull, which reduces the resistance to water flow while maintaining the water's stability. The graphical user interface GUI approach is used to generate and display all of the results, including their readings and graphical analogue meters, as well as the water's impurity limitation points and hazardous level notification. This water quality monitoring boat has a built-in GPS positioning system that indicates the location whenever the water quality changes.. It is shown. These physicochemical properties can be successfully demonstrated by this project, and it is also capable of efficiently showing these readings, according to numerous tests carried out in reservoirs, lakes, and personal water storage tanks.

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Remote Control.

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Knowledge, Virtual autism and its impact on child's brain development

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