Volume 12 | Issue 5 |

 Abstract

Curcuma longa, commonly known as turmeric, has garnered significant attention in recent years due to its diverse pharmacological properties and potential health benefits. This review provides a comprehensive overview of the medicinal properties, bioactive compounds, pharmacokinetics, and therapeutic applications of Curcuma longa. Its principal bioactive component, curcumin, has been extensively studied for its anti-inflammatory, antioxidant, antimicrobial, and anticancer properties. Additionally, Curcuma longa demonstrates promising effects in the management of various chronic diseases such as cardiovascular disorders, neurodegenerative diseases, and metabolic syndromes. Despite its remarkable therapeutic potential, challenges such as poor bioavailability and limited clinical evidence remain. Strategies to enhance the bioavailability of curcumin, including the use of adjuvants and novel delivery systems, are discussed. Furthermore, the safety profile and potential adverse effects associated with Curcuma longa consumption are addressed. Overall, this review underscores the importance of Curcuma longa as a valuable natural remedy and highlights avenues for future research and clinical applications.

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 Keywords

Curcuma longa, Ayurveda, Anti-inflammatory, Antioxidant, Cancer Prevention, Immunomodulatory effect, Neuroprotection.

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The marketed medicine for cancer has various side effects, and the minimization of the side effects using a natural product is rising. In this study, Alangium salviifolium was for its constituents. The alkaloids, namely, Deoxytubulosine and Beta-carboline harmaline, present in plants, have anticancer properties. To understand the anticancer activity of the alkaloids, CADD, a computational-based designing method, was used. The anticancer properties of the compounds using the NPACT database, and the binding affinity study were carried out with six different receptors using the Auto Dock software, with results visualized in Discovery Studio. These results were evaluated with the standard marketed drug Paclitaxel. For the extra benefits, the compounds were modified with Zinc Oxide. After modification, the molecular docking study using the PyRx software results were visualized in Discovery Studio. The pharmacokinetics study using the pkCSM database needs in-vitro validation of Beta-carboline harmaline.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Cancer, Colorectal, Bioinformatics, treatment

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Creative Commons Attribution 4.0 and The Open Definition

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Innovative platform Ensure revolutionizes insurance valuation by offering predictive analytics for a range of commodities. To reliably predict future valuations, our website uses cutting-edge machine learning algorithms, such as time series analysis and regression. Our platform takes in a wide variety of data, processes it using our unique algorithms, and produces accurate forecasts of future values. Users can price their goods more properly, evaluate their options well, and eventually increase profitability because of this predictive capability. To maintain the highest level of accuracy, our machine learning models are regularly updated with fresh data and trained on old data. Regression models allow us to quantify the relationship whereas time series analysis helps us analyze trends and patterns over time. It's a comprehensive solution for insurance companies looking to stay ahead in the competitive market. Join us in redefining insurance valuation and embarking on a journey toward data- driven decision-making.

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Creative Commons Attribution 4.0 and The Open Definition

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Predictive Analytics, Machine Learning, Regression, Time- Series Analysis, Valuation and Pricing.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Versatile phones are utilized all over in this present-day world. The mechanical progression has made everything conceivable beneath one touch. By utilizing the applications introduced within the versatile phones the clients can pay any bills and execute their cash to anybody at their comfort. Increment in utilize of versatile phones and web is the most reason for versatile wallet entrance. This think about was carried out to discover out the factors that influences shoppers inclination towards portable wallet. Employing a organized survey essential information was collected from 160 respondents. The calculate that influences customer inclination and Effect of statistic variables on customer inclination towards versatile wallet were too dissected.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Versatile wallet, Advanced Instalments, Buyer inclination.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The present study aims to find out the effect of continuous yoga practices on emotional maturity of students. It is a comparison study between yoga and non yoga Students in their emotional maturity level. The aim of this research is to find how yogic practices have positively affected emotional health of students. Regular practice of yoga including some basic asanas, pranayama helps students to control over their emotions, better adjustment within society. Study was to assess the impact of yogic practices that include Om chanting, some asanas and pranayama on emotional health of students. In the present study the sample selected by quota sampling method 60 subjects age ranged from (12-18) years. 30 yoga students from Gayatri Vidya Peeth, Gayatrikunj, Shantikung, Haridwar and 30 non-yoga students from Bhagirathi Public School, Haripur Kalan, Haridwar, Uttarakhand. Data collected by distributing questionnaire to respective schools and classes by the help of Ex-post facto research design. Data analysed with the help of t-test. Results revealed the significant high level of emotional maturity in yoga student as compare to non-yoga students.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Emotional disorders, Adolescents, Yoga, Meditation.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

PROTECTION AND PROVISION FOR SMALL BUSINESS IN COMPANIES ACT ,2013:A STUDY

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PROTECTION AND PROVISION FOR SMALL BUSINESS IN COMPANIES ACT ,2013:A STUDY

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Female foeticide remains a persistent issue in India, reflecting deeply ingrained gender biases and social inequities. This abstract explores the multifaceted elements responsible for the prevalence of female foeticide in the country. At its core lies India's patriarchal social structure, which prioritizes male offspring and perpetuates cultural norms valuing sons over daughters. These entrenched beliefs are reinforced by religious and societal customs that celebrate the birth of a son while marginalizing the arrival of a daughter. Socio-economic factors exacerbate the gender imbalance, as poverty and dowry obligations contribute to the perceived burden of raising a daughter. The availability of prenatal sex determination technologies further enables sex-selective abortion, despite legislative efforts to regulate their use. The culmination of these cultural, socio-economic, and systemic factors underscores the complexity of the issue. Addressing female foeticide requires a holistic approach that challenges patriarchal norms, promotes gender equality, and empowers women and girls. Strengthening enforcement mechanisms, improving access to healthcare and education, and fostering economic opportunities for women are essential steps towards combating female foeticide in India. By confronting the root causes and investing in sustainable solutions, India can strive towards a future where every child, regardless of gender, is valued and afforded equal opportunities for a fulfilling life.

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 Keywords

Female foeticide India Gender biases Patriarchal social structure Cultural norms Socio-economic factors Poverty Dowry obligations Prenatal sex determination technologies Legislative efforts Gender equality Empowerment Enforcement mechanisms Healthcare access Education access Economic opportunities Sustainable solutions

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

uttrati ke vyang sahitya me aalochya yugin aarthk paristhitiya

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Creative Commons Attribution 4.0 and The Open Definition

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uttrati ke vyang sahitya me aalochya yugin aarthk paristhitiya

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Creative Commons Attribution 4.0 and The Open Definition

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This paper offers a concise overview of tunnel field-effect transistor (TFET)-based biosensors, detailing their evolution and contemporary applications in biosensing. TFET-based biosensors exhibit notable characteristics such as high sensitivity, affordability, and the ability to detect biomolecules label-free, garnering significant interest. While conventional field-effect transistor biosensors possess advantages, limitations on subthreshold swing, particularly due to various short-channel effects (SS>60 mV/decade), constrain sensitivity, limiting their utility. Ongoing research endeavors aim to address these limitations by enhancing various aspects, with the ultimate aim of devising a device capable of surpassing the drawbacks of established biosensors constructed from multiple transistor devices. This initiative seeks to develop a biosensing platform that optimally combines sensitivity, affordability, and reliability, potentially revolutionizing biosensing applications across various fields.

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 Keywords

Keywords: tunnel field-effect transistor, TFET-based biosensors, biosensing applications, high sensitivity, label-free detection, affordability, subthreshold swing, short-channel effects, biosensor limitations, research, device enhancement, biomolecule detection, biosensing platform

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Creative Commons Attribution 4.0 and The Open Definition

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6G is the sixth-generation mobile system standard currently being developed for wireless communications over cellular data networks in telecommunications.6G, the upcoming sixth-generation mobile system, is being developed to revolutionize wireless communications. As the next step after 5G, it promises to be significantly faster. One of its ambitious goals is to achieve one microsecond latency, making it 1,000 times quicker than the current one millisecond latency. While 6G is still in the research and development phase, its potential to transform connectivity is already generating excitement.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Radio Technology, Future, 4G,5G, 6G, Wireless Communication, Capacity, Latency.

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Creative Commons Attribution 4.0 and The Open Definition