Volume 12 | Issue 6 |

 Abstract

Crinum latifolium Linn., a member of the Amaryllidaceae family, is widely distributed throughout the world's tropics, subtropics, and warm temperate regions. The plant's varied components contain bioactive substances that are used to treat a variety of ailments, including rheumatism, fistula, tumors, earaches, rubefacient, tubercle, and whitlow. The page describes the plant's numerous chemical ingredients, which include alkaloids, flavonoids, terpenoids, and phenolic chemicals. The review also dives into the multiple pharmacological actions linked with Crinum latifolium, including anticancer, anti-inflammatory, antioxidant, and anti-diabetic properties.

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Crinum latifolium, Sudarshan, Pharmacological activities, Phytochemistry, Pharmacognosy

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Viruses, small intracellular parasites composed of RNA or DNA within a protein capsid, necessitate innovative antiviral strategies. Antiviral agents are classified into nonretroviral and retroviral categories, with nonretroviral inhibitors targeting non-HIV infections and antiretroviral drugs focusing on HIV. The Baltimore classification system organizes viruses by genome type and replication method. Viral DNA, once inside the host nucleus, transcribes into mRNA, producing proteins essential for replication, while viral RNA self-translates into necessary enzymes and structural proteins. Famciclovir, an acyclic guanine derivative, converts into the potent antiviral penciclovir upon oral administration. Effective against varicella zoster virus (VZV) and herpes simplex virus (HSV), famciclovir inhibits viral replication by targeting viral DNA polymerase. Clinical trials demonstrate its efficacy in reducing acute symptoms and postherpetic neuralgia, especially in older patients. Famciclovir also shortens genital herpes recurrence intervals, decreases viral shedding, and accelerates lesion healing. With a favorable tolerance profile and simplified dosing, famciclovir offers significant therapeutic advantages over acyclovir. It enhances patient compliance and serves as a crucial option in managing herpesvirus infections, underscoring its role in antiviral therapy and clinical practice.

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Famciclovir, Antiviral, Pharmacological properties, evaluation.

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Background: Badminton is a sport that requires a lot of overhead shoulder motion. Abduction, internal and external rotation of the shoulder joint during shots, lobbing, stroking and smashing were the cause of the injury. Shoulder pain and impingement of the rotator cuff caused by anterior instability of the shoulder joint are frequent problems for the athletes engaged in overhead motion. Painful shoulder conditions have been studied in tennis, baseball and swimming. Materials and Methods: In this study, subjects were randomly assigned to two intervention groups. The Study Design was Experimental in nature. The participants were requrited on the basis of inclusion and exclusion criteria using the purposive sampling. The sample of the study comprised 20 students. Each group consist 10 subjects. The experimental group (A) - 10 by using sleeper stretch and strengthening exercise. Control group (B) - 10 by using general warm up exercise who fulfilled the inclusion and exclusion criteria. Results: The result depict that values of pre-test post- test VAS scores reduced significantly thus concluding experimental Group was significant than control group. The experimental group A is highly significant than control group B. Conclusion: This study concluded that group A intervention ie. modified sleeper stretch with strengthening exercise is effective in reducing pain of shoulder joint among Badminton players during overhead movement after six weeks of intervention.

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Key Word: Sleeper Stretch, VAS, Badminton, Shoulder pain

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In order to minimize detrimental effects on ecosystems and public health, environmental clearance is a crucial regulatory process for the construction of buildings. It guarantees that proposed projects adhere to environmental requirements. This thorough overview looks at all the different facets of environmental clearance, from implementation in practice to legal frameworks. First, it describes the legal prerequisites and regulatory agencies that are involved in environmental clearing, emphasizing national laws, municipal ordinances, and international conventions. Usually, the procedure include filing thorough Environmental Impact Assessments (EIA) that assess potential environmental consequences, putting out mitigation strategies, and holding public meetings. The process steps, such as preliminary screening, scoping, impact analysis, and decision- making, are covered in detail in the overview. It also tackles everyday issues including public opposition, a lack of technical expertise, and bureaucratic delays. It also looks at the advantages of getting environmental clearance, like better community connections, lower liability risks, and increased sustainability. It is also covered how technology may improve the precision and effectiveness of environmental assessments by using remote sensing and Geographic Information Systems (GIS) to streamline the clearance process. Best practices and useful insights can be gained from case studies of effective environmental clearance procedures. The aforementioned instances highlight the significance of openness, involvement of stakeholders, and flexible administration in attaining desired results. To sum up, environmental clearance is a critical safety measure in building construction that strikes a balance between the demands of development and environmental preservation. The building sector can support sustainable development objectives and reduce its environmental impact by upholding strict environmental regulations and encouraging cooperative methods.

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 Keywords

Environmental Clearance, Ecosystems ,Public Health, Regulatory Process, Building Construction, Environmental Requirements, Legal Framework, National Laws, Municipal Ordinances, International Conventions, Environmental Impact Assessments (EIA) ,Mitigation Strategies ,Public Meetings, Preliminary Screening ,Scoping, Impact Analysis, Decision-Making ,Public Opposition, Technical Expertise ,Bureaucratic Delays ,Community Connections, Liability Risks ,Sustainability, Remote Sensing, Geographic Inform

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Global health systems and people have been profoundly impacted by the COVID-19 pandemic, with differing effects on different demographic groups. In the context of Erode, Tamil Nadu, India, this study focuses on the effects of COVID-19 on women's health. The study investigates the impact of the pandemic on women's reproductive, mental, and physical health outcomes. It looks at the difficulties women had getting access to healthcare both before and after COVID-19, taking into account regional cultural norms, healthcare facilities, and socioeconomic issues. In order to obtain a thorough grasp of the problems, both qualitative and quantitative methods are used, including surveys, interviews, and secondary data analysis. With recommendations for practice and policy, the study seeks to provide light on the particular vulnerabilities and resiliency of women in Erode after COVID-19.

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COVID-19, Women's health and Pandemic's effects.

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Employee engagement is an unavoidable function in an organisation to which employees are especially sensitive. So having the correct system in place is unavoidable for any organisation. For employees, the proper engagement system is one that they view as neutral and a true metric for measuring their performance, as well as one that rewards them fairly and without unfairness. The purpose of the study is to determine employees' opinions and perceptions of the existing engagement system. This study seeks to examine the acceptability of the existing system by which they are monitored. The study is conducted by collecting responses from industry employees. The response is obtained via a structured questionnaire. The results were validated using statistical methods

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Employees, Enthusiasm, Passion & Human resources.

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The purpose of this study is to investigate the relationship between worker productivity and mental health at the Erode VMC factory. A qualitative method is used. The data collection strategy used structured one-on-one interviews. The interview transcripts were analysed using an inductive narrative technique. The statistics show a high correlation between employee mental health and job performance. Even though it is rarely specified in corporate policies, the poll found that Erode did not make a sufficient effort "in reality and on the ground" to support its employees' mental health requirements. The findings indicate that low levels of mental health in workers can be reduced.

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Cardiovascular disease, Diabetes and Hypertension.

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A crucial oligo-element is fluoride. It is necessary for the growth of the teeth and the bone. Dental caries is caused by insufficient fluoride ingestion. fluorosis brought on by consuming fluoride in food and water. The transformation of the enamel's hydroxylapatite crystals into fluorapatite depends on fluoride. Because of its strength, this fluorapatite resists demineralization by acid. Conversely, consuming more fluoride from drinking water than is considered safe can result in a range of negative side effects, such as skeletal or dental fluorosis. As a result, the ICMR and WHO advised that 1.5 ppm of fluoride be allowed in drinking water. Varanasi district, India, the study of dental, skeletal, and non-skeletal fluorosis in children (6-12 years) was carried out. Using the DEANS classification, the incidence of dental fluorosis in both dentitions and teeth as well as the contribution of drinking water fluoride levels to the etiology of dental fluorosis were evaluated. Using an ion-specific electrode, the fluoride level of the drinking water, blood, and urine was determined (Thermo Scientific Orion Star A329). Drinking water has fluoride concentrations ranging from 0.7 to 15 parts per million. The youngsters from the study villages had serum and urine with fluoride contents that were abnormally high, according to the analysis of the samples. The elevated illness pattern can also be attributed to higher fluoride concentrations in drinking water.

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Fluorosis, Fluoride, Bone, Urine, Water, Blood, Teeth

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In this paper, we propose a proficient brain tumor revealing strategy, that can distinguish tumor and confine it in the cerebrum MRI pictures. This technique draws out the tumor by utilizing K-means technique which after follows Object labeling calculation. For finer outcome, grouping can be done for recognized districts and apply object naming there, additionally some preprocessing steps are utilized for tumor location reason. Towards the end, the preparation and testing will be performed by SVM, SVM discover the examples of this to use in future and examination reason so it will improve the proficiency of framework and tumor location will get simpler undertaking in field of medicine. It is normal that the trial after effects of the proposed strategy will provide better bring about correlation with other existingsystems.

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MRI, SVM, CT, WM, GM, CSF, K means clustering

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Given a point g and a set M in a Normed linear space, a point of M of minimum distance from g is called a best approximation and the problem of determining such a point is called best approximation problem. Our Main aims are then to investigate important example of such problems, with particular regards of - (1) The existence of best approximation. (2) The uniqueness of best approximation. (3) The characterization of best approximation. (4) The construction of method for determining best approximation. It is clear that the existence of a solution to approximation problems requires certain additional conditions to be satisfied. We will not deal with this aspect of the problem to any great extent, but will be concentrated rather on the treatment of problems for which the normed linear space S, set M and point g are assumed given motivation for the use of any particular norm will however, be given where appropriate. The task of characterizing best approximations is that of deriving potentially useful conditions which a best approximation must satisfy, and which, if satisfied guarantee that a particular approximation is indeed a best approximation. The importance of approximation problems have solution which is characterized by conditions which can be used directly as a means of actually calculating such best approximations. The construction of this solution by their means forms an important part of this paper and results are included in algorithms.

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Best approximation, Normed linear space. Existence, uniqueness, characterization.

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