Volume 9 | Issue 7 |

 Abstract

The liposome is firstly described in 1961 at Babraham institute by Alec D Bangham. The liposomal drug delivery system is an efficient drug delivery system. It is both hydrophilic and lipophilic groups hence it is most convenient to bypass gastric degradation. They are spherical lipid bilayers that consist of an aqueous core. They have a cell membrane-like structure i.e., phospholipid bilayer. Hence, they can easily fuse with cell membranes and enter the cell by endocytosis. In this way, liposome releases their drug in cells. There are various liposomal types according to their uses i.e., immune liposomes, cationic liposomes, long-circulating liposomes, and pH-sensitive liposomes. The cationic liposomes are used to carry DNA. The immune liposomes contain immunological adjuvant which enhances immunological response. pH-sensitive liposomes are used to avoid degradation in lysosomes. Long circulating liposomes are having more molecular weight groups to extend their life. They are widely used in fungal infection, cancer therapy, as DNA vaccine, respiratory diseases, viral diseases, and other diseases. They are recently mostly used in mRNA vaccines and liposomal amphotericin B antifungal drugs. The mRNA vaccine is consisting of lipid nanoparticles, which are made by Pfizer and Moderna companies. The liposomal preparation of amphotericin B reduces nephrotoxicity and amphotericin B is the first line treatment for fungal infections like mucormycosis, systemic fungal infections via intravenously or intrathecally including systemic candida, cryptococcus, blastomycosis, and histoplasmosis17. They are also used in dietary and nutritional supplements recently. They are easy to target specific tissues by passive or active targeting of liposomes. In passive liposomes, there are simple liposomes that are taken up by the liver. Inactive targeting of liposomes, they are targeted in such a way there is the interaction like a drug with receptors (a plug with socket).

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 Keywords

Liposome, structural components of liposomes, Method of preparation of liposomes, Targeting of liposomes.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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 Keywords

components, big data Architecture, Big data security architecture, cloud computing, Big Data Analytics and Technologies for Big Data, MapReduce, Hadoop Map

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 Abstract

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 Keywords

Wind Turbine, Environment and Deforestation

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Social Media can be a great way to engage your student population and ensure they are made aware of student-cantered activities on campus. Another area where the role of social media in education is becoming apparent is in recruitment and admissions. The use of social media is growing and has almost become a utility in many cultures. Colleges tend to be behind the curve in the adoption of using social media in their educational strategy and have not put a lot of time how to overcome the obstacles. Research paper is based on secondary sources.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Student, Social Media, Education, Facebook, Twitter

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Creative Commons Attribution 4.0 and The Open Definition

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This paper assesses the effect of mindfulness and resilience on emotional competence of youth. For this purpose, 112 Youth (56 males and 56 females) took Five facet mindfulness scale(Baer,2006) Brief Resilience scale (Smith, 2008) and Emotional competence scale (Sharma & Bhardwaj,2008). Mindfulness is the basic human ability to be fully aware of their actions and their present which helps in reducing stress, gaining insight and attention. Resilience is the ability to bounce back from adverse situations where as according to Boyatzis et al (1999) emotional competence is how a person demonstrates the competencies that comprises of self-awareness, self-management, social awareness, and social skills at appropriate times. The results indicate a significant positive relationship between mindfulness, resilience and emotional competence. Further mindfulness and resilience positively predicts emotional competence of Youth. No significant gender difference was found with respect to the level of mindfulness, resilience and emotional competence

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 Keywords

: mindfulness, emotional competence, resilience

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Iris cysts are a rare pathology, even more so in children. They develop asymptomatically and can, in some cases, have an impact on the anterior segment (glaucoma, endothelial damage, lens luxation). The treatment is not codified, and remains to be defined on a case-by-case basis, depending on the situation, size and morphology of each cyst. We report the case of a 5-year-old child, with no particular pathological history, who consulted for a bad visual behavior (squinting, approaching objects). The ophthalmological examination revealed a visual acuity of 2/10 in the right eye and 1/10 in the left eye. Slit lamp examination identified pigment epithelial cysts around the pupillary rim of the eyes. The intraoculaire pressure was correct and the lens was clear. The fundus was unremarkable. We completed the examination with a refraction under cycloplegia which showed a myopia of -6 dioptres on the right and -6.50 on the left. The visual acuity increased to 6/10 in both eyes after the refraction.

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 Keywords

Bilateral peripupillary pigment epitheliumiris cysts ,Primitive cysts of the pigment epithelium,iris flocculi

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Sorting is the process of organising data or specific elements into meaningful order so that analysis can be done more efficiently. In this paper, we are intending to introduce a new sorting algorithm called Least-First Sort. In this technique, after each stage of comparison, the smallest element will come first. We have compared the algorithm with other sorting algorithms. We have done the comparison with 10000 to 60000 elements. To the best of our knowledge, the newly proposed algorithm results the least run time than Bubble Sort and Selection Sort.

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 Keywords

sorting; complexity; smallest; algorithm.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Azelnidipine, UV spectroscopy, method development and validation, ? max.

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 Abstract

The problem that policy makers face in kerala now a days is to effectively and efficiently balance the twin themes of economic development and at the same time minimizing the damage to the environment. Kerala, known for its paradoxical social development not matched to economic development, have extensive environmental awareness .along with this they possess societal and environment responsibility .but Kerala today faces problems like pollution , severe traffic noise, non-availability of pure water, limitations in disposal etc. therefore the keralite want to unravel these problems seriously as they affect their well-being. This green awakening force then to avail the green products. Thus the prominence of green products assumes significance during this context. This paper tries to research the factors which impede the demand for environment friendly products by the population of Kerala.

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 Keywords

environment, economic development, environmental awareness, environment friendly goods.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The prediction of stock value is a complex task which needs a robust algorithm background in order to compute the longer-term share prices. Stock prices are correlated within the nature of market; hence it will be difficult to predict the costs. The proposed algorithm using the market data to predict the share price using machine learning techniques like recurrent neural network named as Long Short-Term Memory, in that process weights are corrected for each data points using stochastic gradient descent. This system will provide accurate outcomes in comparison to currently available stock price predictor algorithms. The network is trained and evaluated with various sizes of input data to urge the graphical outcomes.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

close, open, high, low, volume ,LSTM model and regression .

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Creative Commons Attribution 4.0 and The Open Definition